10 Evidence-Based Health Benefits of
Intermittent Fasting
Intermittent
fasting is an eating pattern where you cycle between periods of eating and
fasting. There are many different types of intermittent fasting, such as the
f800 5:2 or our very own 70/30 methods.
Numerous
studies show that it can have powerful benefits for your body and brain. Here
are 10 evidence-based health benefits of intermittent fasting.
1. Intermittent Fasting Changes the Function
of Cells, Genes and Hormones
When
you don’t eat for a while, several things happen in your body.
For
example, your body initiates important cellular repair processes and changes
hormone levels to make stored body fat more accessible.
Here
are some of the changes that occur in your body during fasting:
Insulin
levels: Blood levels of insulin drop significantly, which facilitates fat
burning
Human
growth hormone: The blood levels of growth hormone may increase as much as
5-fold. Higher levels of this hormone facilitate fat burning and muscle gain,
and have numerous other benefits
Cellular
repair: The body induces important cellular repair processes, such as removing
waste material from cells
Gene
expression: There are beneficial changes in several genes and molecules related
to longevity and protection against disease
Many
of the benefits of intermittent fasting are related to these changes in
hormones, gene expression and function of cells.
2. Intermittent Fasting Can Help You
Lose Weight and Belly Fat
Many of those who try intermittent fasting are doing it in order to lose weight. Generally speaking, intermittent fasting will make you eat fewer meals.
Unless
if you compensate by eating much more during the other meals, you will end up
taking in fewer calories.
Additionally,
intermittent fasting enhances hormone function to facilitate weight loss.
Lower
insulin levels, higher growth hormone levels and increased amounts of
norepinephrine (noradrenaline) all increase the breakdown of body fat and
facilitate its use for energy.
For
this reason, short-term fasting actually increases your metabolic rate by
3.6-14%, helping you burn even more calories
In
other words, intermittent fasting works on both sides of the calorie equation.
It boosts your metabolic rate (increases calories out) and reduces the amount
of food you eat (reduces calories in).
According
to a 2014 review of the scientific literature, intermittent fasting can cause
weight loss of 3-8% over 3-24 weeks. This is a huge amount.
The
people also lost 4-7% of their waist circumference, which indicates that they
lost lots of belly fat, the harmful fat in the abdominal cavity that causes
disease.
One
review study also showed that intermittent fasting caused less muscle loss than
continuous calorie restriction
All
things considered, intermittent fasting can be an incredibly powerful weight
loss tool.
3. Intermittent Fasting Can Reduce Insulin
Resistance, Lowering Your Risk of Type 2 Diabetes
Type
2 diabetes has become incredibly common in recent decades.
Its
main feature is high blood sugar levels in the context of insulin resistance.
Anything
that reduces insulin resistance should help lower blood sugar levels and
protect against type 2 diabetes.
Interestingly,
intermittent fasting has been shown to have major benefits for insulin
resistance and lead to an impressive reduction in blood sugar levels.
In
human studies on intermittent fasting, fasting blood sugar has been reduced by
3-6%, while fasting insulin has been reduced by 20-31%.
Intermittent
fasting may be highly protective for people who are at risk of developing type
2 diabetes.
4. Intermittent Fasting Can Reduce Oxidative
Stress and Inflammation in the Body
Oxidative stress is one of the steps towards aging and many chronic diseases
It
involves unstable molecules called free radicals, which react with other
important molecules (like protein and DNA) and damage them
Several
studies show that intermittent fasting may enhance the body’s resistance to
oxidative stress
Additionally,
studies show that intermittent fasting can help fight inflammation, another key
driver of all sorts of common diseases.
5. Intermittent Fasting May be
Beneficial for Heart Health
Heart
disease is currently the world’s biggest killer
It
is known that various health markers (so-called “risk factors”) are associated
with either an increased or decreased risk of heart disease.
Intermittent
fasting has been shown to improve numerous different risk factors, including
blood pressure, total and LDL cholesterol, blood triglycerides, inflammatory
markers and blood sugar levels.
6. Intermittent Fasting Induces
Various Cellular Repair Processes
When we fast, the cells in the body initiate a cellular “waste removal” process called autophagy
This involves the cells breaking down and
metabolizing broken and dysfunctional proteins that build up inside cells over
time.
Increased
autophagy may provide protection against several diseases, including cancer and
Alzheimer’s disease
7. Intermittent Fasting May Help Prevent Cancer
Cancer
is a terrible disease, characterized by uncontrolled growth of cells. Fasting
has been shown to have several beneficial effects on metabolism that may lead
to reduced risk of cancer.
Although
human studies are needed, promising evidence from animal studies indicates that
intermittent fasting may help prevent cancer. There is also some evidence on
human cancer patients, showing that fasting reduced various side effects of
chemotherapy
8. Intermittent Fasting is good for
Your Brain
What is good for the body is often good for the brain as well.
Intermittent
fasting improves various metabolic features known to be important for brain
health.
This
includes reduced oxidative stress, reduced inflammation and a reduction in
blood sugar levels and insulin resistance.
Several
studies in rats have shown that intermittent fasting may increase the growth of
new nerve cells, which should have benefits for brain function
It
also increases levels of a brain hormone called brain-derived neurotrophic
factor (BDNF), a deficiency of which has been implicated in depression and
various other brain problems
Studies
have also shown that intermittent fasting protects against brain damage due to
strokes
9. Intermittent Fasting May Help Prevent
Alzheimer’s Disease
Alzheimer’s
disease is the world’s most common neurodegenerative disease.
There
is no cure available for Alzheimer’s, so preventing it from showing up in the
first place is critical.
A
study in rats shows that intermittent fasting may delay the onset of
Alzheimer’s disease or reduce its severity).
In
a series of case reports, a lifestyle intervention that included daily
short-term fasts was able to significantly improve Alzheimer’s symptoms in 9
out of 10 patients.
Studies
also suggest that fasting may protect against other neurodegenerative diseases,
including Parkinson’s and Huntington’s disease
10. Intermittent Fasting May Extend
Your Lifespan, Helping You Live Longer
One of the most exciting applications of intermittent fasting may be its ability to extend lifespan.
Studies
have shown that intermittent fasting extends lifespan in a similar way as
continuous calorie restriction.
In
some of these studies, the effects were quite dramatic. In one of them, subjects
that fasted every other day lived longer than others who didn’t.
Intermittent
fasting has become very popular among the anti-aging crowd.
Given
the known benefits for metabolism and all sorts of health markers, it makes
sense that intermittent fasting could help you live a longer and healthier
life.






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